Do you have a wasp and hornet problem?
Check out Big Al the Bug Man's tips for wasp and hornet control
It's better to treat these guys with some distance between you and them. The Wasp Freeze and EcoPco Jet-X will let you have that safe distance. It is always better to treat for these guys early in the morning or in the evening when the majority if not all of them are in the nest. Dusting is a good bet to kill the ones that are out foraging but it requires you to get up close to the nest. Whichever way you choose to treat these guys just be very careful, those stings hurt I can tell you from experience.
If you think you have honey bees or Africanized honey bees it will be safer to call a Professional exterminator in your area or a Bee farm to take care of them for you.